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                                Imparting Mosquito Repellent Agents & Assessing Mosquito Repellency on Textile
2014), Phasomkusolsil et al. used cage
30 × 30 × 30 cm dimension (Pha-
somkusolsil and Soonwera 2011),
Anitha et al. used 34 × 32 × 32 cm
cage dimension (Anitha et al. 2011)
and Chang et al. used the
35 × 35 × 35 cm cage dimension
(Chang et al. 2006). Two other studies
reported the used of bigger cage di-
mension, measuring 40 × 30 × 30 cm
by Fei and Xin (2007) and
45 × 45 × 45 cm by (Vigneshkumar
and Vijaykumar Vediappan 2012).
The cage concealed with transparent
mosquito nets for easy observation and
also to keep mosquito remain inside
the cage. It has holes which also cov-
ered with nets for arm accessing pur-
pose. According to WHO (WHO 1996)
conventional standards, the cage
needs to be filled with 200 mosquitoes
that have been starved overnight and
only were supplied with sucrose solu-
tion. Updated standards the use of less-
er number of mos- quitoes in the cage
(as low as 30 mosquitoes), as lower
density provides more accuracy which
better reflect the typical biting environ-
ment encountered during most indoor
and outdoor activities and also to give
a comfortable condition to volunteer.
Volunteers should be preferable not to
be tobacco users and should avoid
using fragrance or repel- lent productsfor 12 h ad during testing. This factor
may alter the person attractiveness to
the mosquitoes and will affect to the
outcome repellency assay. In prepara-
tion of the volunteer, their hand must
be washed with unscented soap and
rinsed with water and placed separat-
ed from each other by =/>20 m away.
The arm covered with gloves or treat-
ed materials of the volunteers will be
inserted into the cages. The left arm
served as control while the right arm
use as treated samples. Both forearms
with untreated and treated materials will
be exposed to the population of mos-
quitoes simultaneously for a period of
3 min. At least two mosquitoes landed
or bite within the 3 min, the test will
continue. If there is no mosquito land-
ed within 3 min, the hand will withdraw
from the cage. The number of mosqui-
to landing will be counted independent-
ly using the digital camera for an ac-
curate result. The exposition is done
every 30 min up to 8 h or until the re-
pellency fails. Each test samples done
in triplicates at 28 ± 2°C and 80 ± 5%
RH with 5 min waiting period between
replicates. The time between applica-
tions of the treated materials recorded
as the protection time. The percentage
of repellency or protection time was
calculated using the formula.
% Mosquito protection =
NCM-OCTOBER 2021
41(U - T)/U × 100
where U corresponds to the number of
mosquitoes on untreated samples or
control samples and T represents the
number of mosquitoes on treated sam-
ples. This is the regularly utilized for-
mulas as stated by Lupi et al. (2013)
although the percentage of repellency
was sometimes calculated with other
formulas, but it will not be discussed
further in this review. The results will
be collected and performed in ANOVA
software for fur- ther analysis. Six
studies (Chang et al. 2006; Fei and Xin
2007; Fradin and Day 2002; Masetti and
Maini 2006; Vigneshkumar and Vijay-
kumar Vediappan 2012; Yang and Ma
2005) demonstrated the use of cage
tests in their study for mosquito repel-
lent.
Cone test
The cone test is formerly the custom
to (Fig. 2) evaluate the toxicity of in-
secticide-treated bed nets against
malaria, which also able investigate the
toxicity of other impregnated (textile)
surfaces. The fabric treated, evaluat-
ed using the WHO cone test following
the standard procedure described in
the WHO 1998: test procedures for in-
secticide resistance monitoring in ma-
laria vectors, bioeficacy and persis-
tance of insecticdes on treated surfac-